Aptamer-enabled uptake of small molecule ligands

The relative ease of isolating aptamers with high specificity for target molecules suggests that molecular recognition may be common in the folds of natural RNAs. We show here that, when expressed in cells, aptamers can increase the intracellular concentrations of their small molecule ligands. We ha...

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Detalles Bibliográficos
Autores principales: Auwardt, Supipi Liyamali, Seo, Yeon-Jung, Ilgu, Muslum, Ray, Judhajeet, Feldges, Robert R., Shubham, Shambhavi, Bendickson, Lee, Levine, Howard A., Nilsen-Hamilton, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200808/
https://www.ncbi.nlm.nih.gov/pubmed/30356136
http://dx.doi.org/10.1038/s41598-018-33887-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200808/
https://www.ncbi.nlm.nih.gov/pubmed/30356136
http://dx.doi.org/10.1038/s41598-018-33887-w

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