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Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis

Non-alcoholic fatty liver disease (NAFLD) results from triglyceride accumulation within the liver and some of them advances to non-alcoholic steatohepatitis (NASH). It is important to note that in NAFLD development, hepatic de novo lipogenesis (DNL) derives from excess carbohydrates and fats under a...

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Detalles Bibliográficos
Autores principales: Lee, Sang R., Kwon, Sun Woo, Kaya, Pelin, Lee, Young Ho, Lee, Jong Geol, Kim, Globinna, Lee, Geun-Shik, Baek, In-Jeoung, Hong, Eui-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200820/
https://www.ncbi.nlm.nih.gov/pubmed/30356113
http://dx.doi.org/10.1038/s41598-018-34148-6