Extracellular Degradation Into Adenosine and the Activities of Adenosine Kinase and AMPK Mediate Extracellular NAD(+)-Produced Increases in the Adenylate Pool of BV2 Microglia Under Basal Conditions

Cumulating evidence has indicated NAD(+) deficiency as a common central pathological factor of multiple diseases and aging. NAD(+) supplement is highly protective in various disease and aging models, while two key questions have remained unanswered: (1) Does extracellular NAD(+) also produce its eff...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Wang, Caixia, Shi, Haibo, Wu, Danhong, Ying, Weihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200843/
https://www.ncbi.nlm.nih.gov/pubmed/30405351
http://dx.doi.org/10.3389/fncel.2018.00343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200843/
https://www.ncbi.nlm.nih.gov/pubmed/30405351
http://dx.doi.org/10.3389/fncel.2018.00343

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