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Antibody Epitope Specificity for dsDNA Phosphate Backbone Is an Intrinsic Property of the Heavy Chain Variable Germline Gene Segment Used
Analysis of protein sequences by the informational spectrum method (ISM) enables characterization of their specificity according to encoded information represented with defined frequency (F). Our previous data showed that F(0.367) is characteristic for variable heavy chain (VH) domains (a combinatio...
Autores principales: | Srdic-Rajic, Tatjana, Kohler, Heinz, Jurisic, Vladimir, Metlas, Radmila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200867/ https://www.ncbi.nlm.nih.gov/pubmed/30405605 http://dx.doi.org/10.3389/fimmu.2018.02378 |
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