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The DNA damage response in immunotherapy and radiation
PURPOSE: Deficiencies in DNA damage repair (DDR) and response represent a common alteration in tumors, and exploitation of this feature using therapeutics has become more prominent. METHODS AND MATERIALS: Recent work has highlighted the important interaction between DDR defects, as well as DDR targe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200889/ https://www.ncbi.nlm.nih.gov/pubmed/30370352 http://dx.doi.org/10.1016/j.adro.2018.08.017 |