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Bordetella pertussis Whole Cell Immunization, Unlike Acellular Immunization, Mimics Naïve Infection by Driving Hematopoietic Stem and Progenitor Cell Expansion in Mice

Hematopoietic stem and progenitor cell (HSPC) compartments are altered to direct immune responses to infection. Their roles during immunization are not well-described. To elucidate mechanisms for waning immunity following immunization with acellular vaccines (ACVs) against Bordetella pertussis (Bp),...

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Detalles Bibliográficos
Autores principales: Varney, Melinda E., Boehm, Dylan T., DeRoos, Katherine, Nowak, Evan S., Wong, Ting Y., Sen-Kilic, Emel, Bradford, Shebly D., Elkins, Cody, Epperly, Matthew S., Witt, William T., Barbier, Mariette, Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200895/
https://www.ncbi.nlm.nih.gov/pubmed/30405604
http://dx.doi.org/10.3389/fimmu.2018.02376