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Role of the immunosuppressive microenvironment in immunotherapy

Immunotherapy is reshaping cancer treatment paradigms; however, response rates to immune therapies are low and depend on the host's pre-existing antitumor immunity. The tumor microenvironment is comprised of malignant cells, stroma, and extracellular molecules and can hinder immune control of t...

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Detalles Bibliográficos
Autores principales: Tormoen, Garth W., Crittenden, Marka R., Gough, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200899/
https://www.ncbi.nlm.nih.gov/pubmed/30370351
http://dx.doi.org/10.1016/j.adro.2018.08.018