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The Capsule of Cryptococcus neoformans Modulates Phagosomal pH through Its Acid-Base Properties

Phagosomal acidification is a critical cellular mechanism for the inhibition and killing of ingested microbes by phagocytic cells. The acidic environment activates microbicidal proteins and creates an unfavorable environment for the growth of many microbes. Consequently, numerous pathogenic microbes...

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Detalles Bibliográficos
Autores principales: De Leon-Rodriguez, Carlos M., Fu, Man Shun, Çorbali, M. Osman, Cordero, Radames J. B., Casadevall, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200979/
https://www.ncbi.nlm.nih.gov/pubmed/30355667
http://dx.doi.org/10.1128/mSphere.00437-18