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Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling

The first line treatment for uncomplicated falciparum malaria is artemisinin-based combination therapy (ACT), which consists of an artemisinin derivative coadministered with a longer-acting partner drug. However, the spread of Plasmodium falciparum resistant to both artemisinin and its partner drugs...

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Detalles Bibliográficos
Autores principales: Dini, Saber, Zaloumis, Sophie, Cao, Pengxing, Price, Ric N., Fowkes, Freya J. I., van der Pluijm, Rob W., McCaw, James M., Simpson, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201091/
https://www.ncbi.nlm.nih.gov/pubmed/30150462
http://dx.doi.org/10.1128/AAC.01068-18