Modeling Skeletal Muscle Laminopathies Using Human Induced Pluripotent Stem Cells Carrying Pathogenic LMNA Mutations

Laminopathies are a clinically heterogeneous group of disorders caused by mutations in LMNA. The main proteins encoded by LMNA are Lamin A and C, which together with Lamin B1 and B2, form the nuclear lamina: a mesh-like structure located underneath the inner nuclear membrane. Laminopathies show stri...

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Detalles Bibliográficos
Autores principales: Steele-Stallard, Heather B., Pinton, Luca, Sarcar, Shilpita, Ozdemir, Tanel, Maffioletti, Sara M., Zammit, Peter S., Tedesco, Francesco Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201196/
https://www.ncbi.nlm.nih.gov/pubmed/30405424
http://dx.doi.org/10.3389/fphys.2018.01332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201196/
https://www.ncbi.nlm.nih.gov/pubmed/30405424
http://dx.doi.org/10.3389/fphys.2018.01332

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