Pharmacological characterization of hetrombopag, a novel orally active human thrombopoietin receptor agonist

Nonpeptide thrombopoietin receptor (TPOR/MPL) agonists, such as eltrombopag, have been used to treat thrombocytopenia of various aetiologies. Here, we investigated the pharmacological properties of hetrombopag, a new orally active small‐molecule TPOR agonist, in preclinical models. Hetrombopag speci...

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Detalles Bibliográficos
Autores principales: Xie, Chengying, Zhao, Huajun, Bao, Xubin, Fu, Haoyu, Lou, Liguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201220/
https://www.ncbi.nlm.nih.gov/pubmed/30156363
http://dx.doi.org/10.1111/jcmm.13809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201220/
https://www.ncbi.nlm.nih.gov/pubmed/30156363
http://dx.doi.org/10.1111/jcmm.13809

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