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Down‐regulated in OA cartilage, SFMBT2 contributes to NF‐κB‐mediated ECM degradation

The interplay between anabolic and catabolic factors regulates cartilage matrix homoeostasis. In OA, this balance is disrupted which results in cartilage degradation involving a plethora of inflammatory factors. Here, we identify a novel gene “Scm‐like with four MBT domains protein 2” (SFMBT2) negat...

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Detalles Bibliográficos
Autores principales: Hussain, Safdar, Sun, Mengyao, Min, Zixin, Guo, Yuanxu, Xu, Jing, Mushtaq, Nosheen, Heng, Lisong, Huang, Huang, Zhao, Yitong, Yuan, Ying, Hussain, Nazim, Zhang, Fujun, Han, Yan, Xu, Peng, Sun, Jian, Lu, Shemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201222/
https://www.ncbi.nlm.nih.gov/pubmed/30133133
http://dx.doi.org/10.1111/jcmm.13826