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Down‐regulated in OA cartilage, SFMBT2 contributes to NF‐κB‐mediated ECM degradation
The interplay between anabolic and catabolic factors regulates cartilage matrix homoeostasis. In OA, this balance is disrupted which results in cartilage degradation involving a plethora of inflammatory factors. Here, we identify a novel gene “Scm‐like with four MBT domains protein 2” (SFMBT2) negat...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201222/ https://www.ncbi.nlm.nih.gov/pubmed/30133133 http://dx.doi.org/10.1111/jcmm.13826 |