Plectin protects podocytes from adriamycin‐induced apoptosis and F‐actin cytoskeletal disruption through the integrin α6β4/FAK/p38 MAPK pathway

Podocyte injury is an early pathological change characteristic of various glomerular diseases, and apoptosis and F‐actin cytoskeletal disruption are typical features of podocyte injury. In this study, we found that adriamycin (ADR) treatment resulted in typical podocyte injury and repressed plectin...

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Detalles Bibliográficos
Autores principales: Ni, Yongliang, Wang, Xin, Yin, Xiaoxuan, Li, Yan, Liu, Xigao, Wang, Haixin, Liu, Xiangjv, Zhang, Jun, Gao, Haiqing, Shi, Benkang, Zhao, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201223/
https://www.ncbi.nlm.nih.gov/pubmed/30187999
http://dx.doi.org/10.1111/jcmm.13816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201223/
https://www.ncbi.nlm.nih.gov/pubmed/30187999
http://dx.doi.org/10.1111/jcmm.13816

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