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Plectin protects podocytes from adriamycin‐induced apoptosis and F‐actin cytoskeletal disruption through the integrin α6β4/FAK/p38 MAPK pathway
Podocyte injury is an early pathological change characteristic of various glomerular diseases, and apoptosis and F‐actin cytoskeletal disruption are typical features of podocyte injury. In this study, we found that adriamycin (ADR) treatment resulted in typical podocyte injury and repressed plectin...
Autores principales: | Ni, Yongliang, Wang, Xin, Yin, Xiaoxuan, Li, Yan, Liu, Xigao, Wang, Haixin, Liu, Xiangjv, Zhang, Jun, Gao, Haiqing, Shi, Benkang, Zhao, Shaohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201223/ https://www.ncbi.nlm.nih.gov/pubmed/30187999 http://dx.doi.org/10.1111/jcmm.13816 |
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