Exosomal miR‐95‐5p regulates chondrogenesis and cartilage degradation via histone deacetylase 2/8

MicroRNAs play critical roles in the pathogenesis of osteoarthritis, the most common chronic degenerative joint disease. Exosomes derived from miR‐95‐5p‐overexpressing primary chondrocytes (AC‐miR‐95‐5p) may be effective in treating osteoarthritis. Increased expression of HDAC2/8 occurs in the tissu...

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Detalles Bibliográficos
Autores principales: Mao, Guping, Hu, Shu, Zhang, Ziji, Wu, Peihui, Zhao, Xiaoyi, Lin, Ruifu, Liao, Weiming, Kang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201229/
https://www.ncbi.nlm.nih.gov/pubmed/30063117
http://dx.doi.org/10.1111/jcmm.13808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201229/
https://www.ncbi.nlm.nih.gov/pubmed/30063117
http://dx.doi.org/10.1111/jcmm.13808

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