Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats

Intervertebral disc degeneration (IVDD) is one of the major causes of low back pain. Polydatin (PD) has been shown to exert multiple pharmacological effects on different diseases; here, we test the therapeutic potential of PD for IVDD. In in‐vitro experiments, we confirmed PD is nontoxic to nucleus...

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Detalles Bibliográficos
Autores principales: Wang, Jianle, Huang, Chongan, Lin, Zongze, Pan, Xiangxiang, Chen, Jiaoxiang, Zheng, Gang, Tian, Naifeng, Yan, Yingzhao, Zhang, Zengjie, Hu, Jianing, Cheng, Pu, Wang, Xiangyang, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201341/
https://www.ncbi.nlm.nih.gov/pubmed/30358118
http://dx.doi.org/10.1111/jcmm.13848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201341/
https://www.ncbi.nlm.nih.gov/pubmed/30358118
http://dx.doi.org/10.1111/jcmm.13848

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