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PLK1 inhibitor facilitates the suppressing effect of temozolomide on human brain glioma stem cells

Glioblastoma is the most frequent and most aggressive brain tumour in adults. Temozolomide is an oral chemotherapy drug and one of the major components of chemotherapy regimens used as a treatment of some brain cancers. We examined the tolerance of stem cells isolated from glioma cell line U87 and U...

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Detalles Bibliográficos
Autores principales: Liu, Naijie, Hu, Guozhang, Wang, Han, Li, Zhaohui, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201353/
https://www.ncbi.nlm.nih.gov/pubmed/30133120
http://dx.doi.org/10.1111/jcmm.13793