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Epithelial down‐regulation of the miR‐200 family in fibrostenosing Crohn's disease is associated with features of epithelial to mesenchymal transition

Intestinal mesenchymal cells deposit extracellular matrix in fibrotic Crohn's disease (CD). The contribution of epithelial to mesenchymal transition (EMT) to the mesenchymal cell pool in CD fibrosis remains obscure. The miR‐200 family regulates fibrosis‐related EMT in organs other than the gut....

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Detalles Bibliográficos
Autores principales: Mehta, Shameer J., Lewis, Amy, Nijhuis, Anke, Jeffery, Rosemary, Biancheri, Paolo, Di Sabatino, Antonio, Feakins, Roger, Silver, Andrew, Lindsay, James Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201355/
https://www.ncbi.nlm.nih.gov/pubmed/30188001
http://dx.doi.org/10.1111/jcmm.13836