rSjP40 suppresses hepatic stellate cell activation by promoting microRNA‐155 expression and inhibiting STAT5 and FOXO3a expression

Activation of hepatic stellate cells (HSCs) is the central event of the evolution of hepatic fibrosis. Schistosomiasis is one of the pathogenic factors which could induce hepatic fibrosis. Previous studies have shown that recombinant Schistosoma japonicum egg antigen P40 (rSjP40) can inhibit the act...

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Detalles Bibliográficos
Autores principales: Zhu, Dandan, Yang, Chunzhao, Shen, Pei, Chen, Liuting, Chen, Jinling, Sun, Xiaolei, Duan, Lian, Zhang, Li, Zhu, Jinhua, Duan, Yinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201359/
https://www.ncbi.nlm.nih.gov/pubmed/30091834
http://dx.doi.org/10.1111/jcmm.13819