Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts

Subcellular distribution of mitochondria in neurons is crucial for meeting the energetic demands, as well as the necessity to buffer Ca(2+) within the axon, dendrites and synapses. Mitochondrial impairment is an important feature of Parkinson disease (PD), in which both familial parkinsonism genes D...

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Detalles Bibliográficos
Autores principales: Parrado‐Fernández, Cristina, Schneider, Bernadette, Ankarcrona, Maria, Conti, Melissa M., Cookson, Mark R., Kivipelto, Miia, Cedazo‐Mínguez, Ángel, Sandebring‐Matton, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201361/
https://www.ncbi.nlm.nih.gov/pubmed/30133157
http://dx.doi.org/10.1111/jcmm.13815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201361/
https://www.ncbi.nlm.nih.gov/pubmed/30133157
http://dx.doi.org/10.1111/jcmm.13815

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