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Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts
Subcellular distribution of mitochondria in neurons is crucial for meeting the energetic demands, as well as the necessity to buffer Ca(2+) within the axon, dendrites and synapses. Mitochondrial impairment is an important feature of Parkinson disease (PD), in which both familial parkinsonism genes D...
Autores principales: | Parrado‐Fernández, Cristina, Schneider, Bernadette, Ankarcrona, Maria, Conti, Melissa M., Cookson, Mark R., Kivipelto, Miia, Cedazo‐Mínguez, Ángel, Sandebring‐Matton, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201361/ https://www.ncbi.nlm.nih.gov/pubmed/30133157 http://dx.doi.org/10.1111/jcmm.13815 |
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