Polarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology

The transepithelial potential difference (TEP) across the retinal pigment epithelial (RPE) is dependent on ionic pumps and tight junction “seals” between epithelial cells. RPE cells release neurotrophic growth factors such as pigment epithelial derived factor (PEDF), which is reduced in age‐related...

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Detalles Bibliográficos
Autores principales: Cao, Lin, Liu, Jie, Pu, Jin, Milne, Gillian, Chen, Mei, Xu, Heping, Shipley, Alan, Forrester, John V, McCaig, Colin D, Lois, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201363/
https://www.ncbi.nlm.nih.gov/pubmed/30160348
http://dx.doi.org/10.1111/jcmm.13829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201363/
https://www.ncbi.nlm.nih.gov/pubmed/30160348
http://dx.doi.org/10.1111/jcmm.13829

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