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Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1

Smoking is a major preventable risk factor for atherosclerosis. However, the causative link between cigarette smoke and atherosclerosis remains to be established. The objective of this study is to characterize the role of GTP cyclohydrolase 1 (GTPCH1), the rate‐limiting enzyme for de novo tetrahydro...

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Detalles Bibliográficos
Autores principales: Li, Jingyuan, Liu, Shangming, Cao, Guangqing, Sun, Yuanyuan, Chen, Weiqian, Dong, Fajin, Xu, Jinfeng, Zhang, Cheng, Zhang, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201367/
https://www.ncbi.nlm.nih.gov/pubmed/30091833
http://dx.doi.org/10.1111/jcmm.13812