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SCN1Bβ mutations that affect their association with Kv4.3 underlie early repolarization syndrome
BACKGROUND: Abnormal cardiac ion channels current, including transient outward potassium current (I(to)), is associated with early repolarization syndrome (ERS). Previous studies showed that mutations in SCN1Bβ both to increase the I(to) current and to decrease the sodium current. Yet its role in ER...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201368/ https://www.ncbi.nlm.nih.gov/pubmed/30160358 http://dx.doi.org/10.1111/jcmm.13839 |