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SCN1Bβ mutations that affect their association with Kv4.3 underlie early repolarization syndrome

BACKGROUND: Abnormal cardiac ion channels current, including transient outward potassium current (I(to)), is associated with early repolarization syndrome (ERS). Previous studies showed that mutations in SCN1Bβ both to increase the I(to) current and to decrease the sodium current. Yet its role in ER...

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Detalles Bibliográficos
Autores principales: Yao, Hao, Fan, Jun, Cheng, Yun‐Jiu, Chen, Xu‐Miao, Ji, Cheng‐Cheng, Liu, Li‐Juan, Zheng, Zi‐Heng, Wu, Su‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201368/
https://www.ncbi.nlm.nih.gov/pubmed/30160358
http://dx.doi.org/10.1111/jcmm.13839

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