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PKCα replaces AMPK to regulate mitophagy: Another PEDF role on ischaemic cardioprotection

Both decreased autophagy positive regulator AMP activated protein kinase (AMPK) level and promoted mitophagy are observed in oxygen‐glucose deprivation (OGD) cardiomyocytes treated with pigment epithelium‐derived factor (PEDF). This contradictory phenomenon and its underlying mechanisms have not bee...

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Detalles Bibliográficos
Autores principales: Miao, Haoran, Qiu, Fan, Huang, Bing, Liu, Xiucheng, Zhang, Hao, Liu, Zhiwei, Yuan, Yanliang, Zhao, Qixiang, Zhang, Hu, Dong, Hongyan, Zhang, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201373/
https://www.ncbi.nlm.nih.gov/pubmed/30230261
http://dx.doi.org/10.1111/jcmm.13849