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P‐Glycoprotein (P‐gp)/ABCB1 plays a functional role in extravillous trophoblast (EVT) invasion and is decreased in the pre‐eclamptic placenta

Dysregulation of trophoblast differentiation is implicated in the placental pathologies of intrauterine growth restriction and pre‐eclampsia. P‐glycoprotein (P‐gp encoded by ABCB1) is an ATP‐binding cassette transporter present in the syncytiotrophoblast layer of the placenta where it acts as a mole...

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Detalles Bibliográficos
Autores principales: Dunk, Caroline E., Pappas, Jane J., Lye, Phetcharawan, Kibschull, Mark, Javam, Mohsen, Bloise, Enrrico, Lye, Stephen J., Szyf, Moshe, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201374/
https://www.ncbi.nlm.nih.gov/pubmed/30256530
http://dx.doi.org/10.1111/jcmm.13810