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Variants at the APOE/C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High‐Density Lipoprotein Cholesterol

BACKGROUND: Macrophage cholesterol efflux to high‐density lipoproteins (HDLs) is the first step of reverse cholesterol transport. The cholesterol efflux capacity (CEC) of HDL particles is a protective risk factor for coronary artery disease independent of HDL cholesterol levels. Using a genome‐wide...

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Detalles Bibliográficos
Autores principales: Low‐Kam, Cécile, Rhainds, David, Lo, Ken Sin, Barhdadi, Amina, Boulé, Marie, Alem, Sonia, Pedneault‐Gagnon, Valérie, Rhéaume, Eric, Dubé, Marie‐Pierre, Busseuil, David, Hegele, Robert A., Lettre, Guillaume, Tardif, Jean‐Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201388/
https://www.ncbi.nlm.nih.gov/pubmed/30369316
http://dx.doi.org/10.1161/JAHA.118.009545