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Activin Receptor‐Like Kinase 4 Haplodeficiency Mitigates Arrhythmogenic Atrial Remodeling and Vulnerability to Atrial Fibrillation in Cardiac Pathological Hypertrophy

BACKGROUND: Activin receptor‐like kinase 4 (ALK4) is highly expressed in mammal heart. Atrial fibrillation (AF) is closely related to ventricular pressure overload. Because pressure overload increases atrial pressure and leads to atrial remodeling, it would be informative to know whether ALK4 exerts...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Chen, Yihe, Zhang, Daoliang, Li, Changyi, Chen, Xiaoqing, Hou, Jianwen, Fei, Yudong, Wang, Yuepeng, Li, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201394/
https://www.ncbi.nlm.nih.gov/pubmed/30369314
http://dx.doi.org/10.1161/JAHA.118.008842