Soluble CD74 Reroutes MIF/CXCR4/AKT‐Mediated Survival of Cardiac Myofibroblasts to Necroptosis

BACKGROUND: Although macrophage migration inhibitory factor (MIF) has been demonstrated to mediate cardioprotection in ischemia/reperfusion injury and antagonize fibrotic effects through its receptor, CD74, the function of the soluble CD74 receptor ectodomain (sCD74) and its interaction with circula...

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Detalles Bibliográficos
Autores principales: Soppert, Josefin, Kraemer, Sandra, Beckers, Christian, Averdunk, Luisa, Möllmann, Julia, Denecke, Bernd, Goetzenich, Andreas, Marx, Gernot, Bernhagen, Jürgen, Stoppe, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201423/
https://www.ncbi.nlm.nih.gov/pubmed/30371153
http://dx.doi.org/10.1161/JAHA.118.009384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201423/
https://www.ncbi.nlm.nih.gov/pubmed/30371153
http://dx.doi.org/10.1161/JAHA.118.009384

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