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Soluble CD74 Reroutes MIF/CXCR4/AKT‐Mediated Survival of Cardiac Myofibroblasts to Necroptosis
BACKGROUND: Although macrophage migration inhibitory factor (MIF) has been demonstrated to mediate cardioprotection in ischemia/reperfusion injury and antagonize fibrotic effects through its receptor, CD74, the function of the soluble CD74 receptor ectodomain (sCD74) and its interaction with circula...
Autores principales: | Soppert, Josefin, Kraemer, Sandra, Beckers, Christian, Averdunk, Luisa, Möllmann, Julia, Denecke, Bernd, Goetzenich, Andreas, Marx, Gernot, Bernhagen, Jürgen, Stoppe, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201423/ https://www.ncbi.nlm.nih.gov/pubmed/30371153 http://dx.doi.org/10.1161/JAHA.118.009384 |
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