Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats

BACKGROUND: Renal hypoxia, implicated as crucial factor in onset and progression of chronic kidney disease, may be attributed to reduced nitric oxide because nitric oxide dilates vasculature and inhibits mitochondrial oxygen consumption. We hypothesized that chronic nitric oxide synthase inhibition...

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Detalles Bibliográficos
Autores principales: Emans, Tonja W., Janssen, Ben J., Joles, Jaap A., Krediet, C.T. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201463/
https://www.ncbi.nlm.nih.gov/pubmed/30371226
http://dx.doi.org/10.1161/JAHA.118.009501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201463/
https://www.ncbi.nlm.nih.gov/pubmed/30371226
http://dx.doi.org/10.1161/JAHA.118.009501

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