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Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses

BACKGROUND: Total flavonoids of Rhododendron (TFR) is extracted from Rhododendron, a herbal medicine widely used in China. The main components are flavone compounds such as warfarin, rutin, quercetin, and hyperoside. We investigated the role of TRPV4 channel in the TFR induced endothelium-dependent...

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Detalles Bibliográficos
Autores principales: Han, Jun, Xu, Hang-Hang, Chen, Xiao-Long, Hu, Hao-Ran, Hu, Kun-Mei, Chen, Zhi-Wu, He, Guo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201489/
https://www.ncbi.nlm.nih.gov/pubmed/30405745
http://dx.doi.org/10.1155/2018/8919867