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Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses
BACKGROUND: Total flavonoids of Rhododendron (TFR) is extracted from Rhododendron, a herbal medicine widely used in China. The main components are flavone compounds such as warfarin, rutin, quercetin, and hyperoside. We investigated the role of TRPV4 channel in the TFR induced endothelium-dependent...
Autores principales: | Han, Jun, Xu, Hang-Hang, Chen, Xiao-Long, Hu, Hao-Ran, Hu, Kun-Mei, Chen, Zhi-Wu, He, Guo-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201489/ https://www.ncbi.nlm.nih.gov/pubmed/30405745 http://dx.doi.org/10.1155/2018/8919867 |
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