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An integrated approach of bioinformatic prediction and in vitro analysis identified that miR-34a targets MET and AXL in triple-negative breast cancer

BACKGROUND: Breast cancer is the most prevalent cancer among women, and AXL and MET are the key genes in the PI3K/AKT/mTOR pathway as critical elements in proliferation and invasion of cancer cells. MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of genes. METHODS: Bioinformat...

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Detalles Bibliográficos
Autores principales: Hajalirezay Yazdi, Shadan, Paryan, Mahdi, Mohammadi-Yeganeh, Samira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201502/
https://www.ncbi.nlm.nih.gov/pubmed/30386383
http://dx.doi.org/10.1186/s11658-018-0116-y