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EphrinB/EphB forward signaling in Müller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model

It was previously shown that EphB/ephrinB reverse signaling in retinal ganglion cells (RGCs) is activated and involved in RGC apoptosis in a rat chronic ocular hypertension (COH) model. In the present work, we first show that ephrinB/EphB forward signaling was activated in COH retinas, and RGC apopt...

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Detalles Bibliográficos
Autores principales: Liu, Shu-Ting, Zhong, Shu-Min, Li, Xue-Yan, Gao, Feng, Li, Fang, Zhang, Meng-Lu, Zhu, Ke, Sun, Xing-Huai, Wang, Xin, Miao, Yanying, Yang, Xiong-Li, Wang, Zhongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201539/
https://www.ncbi.nlm.nih.gov/pubmed/30355282
http://dx.doi.org/10.1186/s40478-018-0618-x