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Isolation and characterization of malaria PfHRP2 specific V(NAR) antibody fragments from immunized shark phage display library

BACKGROUND: Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. The variable region of the receptor (V(NAR)) from shark has a potential as altern...

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Detalles Bibliográficos
Autores principales: Leow, Chiuan Herng, Fischer, Katja, Leow, Chiuan Yee, Braet, Katleen, Cheng, Qin, McCarthy, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201582/
https://www.ncbi.nlm.nih.gov/pubmed/30355309
http://dx.doi.org/10.1186/s12936-018-2531-y