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In silico model-guided identification of transcriptional regulator targets for efficient strain design

BACKGROUND: Cellular metabolism is tightly regulated by hard-wired multiple layers of biological processes to achieve robust and homeostatic states given the limited resources. As a result, even the most intuitive enzyme-centric metabolic engineering endeavours through the up-/down-regulation of mul...

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Detalles Bibliográficos
Autores principales:	Koduru, Lokanand, Lakshmanan, Meiyappan, Lee, Dong-Yup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201637/ https://www.ncbi.nlm.nih.gov/pubmed/30359263 http://dx.doi.org/10.1186/s12934-018-1015-7

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