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Facile saccharide-free mimetics that recapitulate key features of glycosaminoglycan sulfation patterns

Controlling glycosaminoglycan (GAG) activity to exploit its immense potential in biology ultimately requires facile manipulation of sulfation patterns associated with GAGs. However, satisfying this requirement in full remains challenging, given that synthesis of GAGs is technically arduous while con...

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Detalles Bibliográficos
Autores principales: Lim, Teck Chuan, Cai, Shuting, Huber, Roland G., Bond, Peter J., Siew Chia, Priscilla Xian, Khou, Siv Ly, Gao, Shujun, Lee, Su Seong, Lee, Song-Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201788/
https://www.ncbi.nlm.nih.gov/pubmed/30429999
http://dx.doi.org/10.1039/c8sc02303d