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Borneol and Α-asarone as adjuvant agents for improving blood–brain barrier permeability of puerarin and tetramethylpyrazine by activating adenosine receptors

Puerarin (PUE) and tetramethylpyrazine (TMP) are central nervous system (CNS) drugs used in cerebrovascular diseases. Poor brain–blood barrier (BBB) permeability limited their clinical application. Borneol and α-asarone have been proposed as an oral brain-targeting enhancer. In this study, we aimed...

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Detalles Bibliográficos
Autores principales: Wu, Jun-Yong, Li, Yong-Jiang, Yang, Le, Hu, Yi-Yun, Hu, Xiong-Bin, Tang, Tian-Tian, Wang, Jie-Min, Liu, Xin-Yi, Xiang, Da-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201807/
https://www.ncbi.nlm.nih.gov/pubmed/30338713
http://dx.doi.org/10.1080/10717544.2018.1516005