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N-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed mice

Obesity and insulin resistance are primary risk factors for Non-Alcoholic Fatty Liver Disease (NAFLD). NAFLD is generally exhibited by non-progressive simple steatosis. However, a significant subset of patient’s progress to nonalcoholic steatohepatitis (NASH) that is defined by the presence of steat...

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Detalles Bibliográficos
Autores principales: Bhagat, Hiral A., Compton, Sarah A., Musso, David L., Laudeman, Christopher P., Jackson, Kimberly M. P., Yi, Na Young, Nierobisz, Lidia S., Forsberg, Lawrence, Brenman, Jay E., Sexton, Jonathan Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201879/
https://www.ncbi.nlm.nih.gov/pubmed/30359371
http://dx.doi.org/10.1371/journal.pone.0204605