The zebrafish orthologue of familial Alzheimer’s disease gene PRESENILIN 2 is required for normal adult melanotic skin pigmentation

Alzheimer’s disease is the most common form of age-related dementia. At least 15 mutations in the human gene PRESENILIN 2 (PSEN2) have been found to cause familial Alzheimer’s disease (fAD). Zebrafish possess an orthologous gene, psen2, and present opportunities for investigation of PRESENILIN funct...

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Detalles Bibliográficos
Autores principales: Jiang, Haowei, Newman, Morgan, Lardelli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201934/
https://www.ncbi.nlm.nih.gov/pubmed/30359395
http://dx.doi.org/10.1371/journal.pone.0206155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201934/
https://www.ncbi.nlm.nih.gov/pubmed/30359395
http://dx.doi.org/10.1371/journal.pone.0206155

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