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Presence of aberrant epididymal tubules revealing undifferentiated epithelial cells and absence of spermatozoa in a combined neuraminidase-3 and -4 deficient adult mouse model

Mammalian neuraminidases are responsible for the removal of sialic acids from glycoproteins and glycolipids and function in a variety of biological phenomena such as lysosomal catabolism and control of cell differentiation and growth. Disruption of Neu3 and Neu4 genes has led to the generation of a...

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Detalles Bibliográficos
Autores principales: Oliveira, Regiana, Hermo, Louis, Pshezhetsky, Alexey V., Morales, Carlos R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201937/
https://www.ncbi.nlm.nih.gov/pubmed/30359429
http://dx.doi.org/10.1371/journal.pone.0206173