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HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay

Human Immunodeficiency Virus-1 (HIV-1) entry is dependent on the envelope glycoprotein (Env) that is present on the virion and facilitates fusion between the envelope and the cellular membrane. The protein consists of two subunits, gp120 and gp41, with the former required for binding the CD4 recepto...

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Detalles Bibliográficos
Autores principales: Yang, Edward, Gardner, Matthew R., Zhou, Amber S., Farzan, Michael, Arvin, Ann M., Oliver, Stefan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201953/
https://www.ncbi.nlm.nih.gov/pubmed/30359435
http://dx.doi.org/10.1371/journal.pone.0206365