BML-111 suppresses TGF-β1-induced lung fibroblast activation in vitro and decreases experimental pulmonary fibrosis in vivo

Pulmonary fibrosis is an aggressive end-stage disease. Transforming growth factor-β1 (TGF-β1) mediates lung fibroblast activation and is essential for the progress of pulmonary fibrosis. BML-111, a lipoxinA(4 )(LXA(4)) receptor (ALX) agonist, has been reported to possess anti-fibrotic properties. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Yu-Dong, Luo, Zhen-Long, Chen, Chun-Xiu, Li, Bo, Gong, Jie, Wang, Ya-Xin, Chen, Lin, Yao, Shang-Long, Shang, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202103/
https://www.ncbi.nlm.nih.gov/pubmed/30280199
http://dx.doi.org/10.3892/ijmm.2018.3914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202103/
https://www.ncbi.nlm.nih.gov/pubmed/30280199
http://dx.doi.org/10.3892/ijmm.2018.3914

Ejemplares similares