O-GlcNAc-modified SNAP29 inhibits autophagy-mediated degradation via the disturbed SNAP29-STX17-VAMP8 complex and exacerbates myocardial injury in type I diabetic rats

The O-linked β-N-acetylglucosamine (O-GlcNAc) modification and autophagy are associated with diabetic myocardial injury, however, the molecular mechanisms between the two processes remain to be fully elucidated. The purpose of the present study was to elucidate the molecular regulation of autophagy...

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Detalles Bibliográficos
Autores principales: Huang, Lin, Yuan, Ping, Yu, Peng, Kong, Qiling, Xu, Zixuan, Yan, Xia, Shen, Yang, Yang, Juesheng, Wan, Rong, Hong, Kui, Tang, Yanhua, Hu, Jinzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202107/
https://www.ncbi.nlm.nih.gov/pubmed/30221662
http://dx.doi.org/10.3892/ijmm.2018.3866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202107/
https://www.ncbi.nlm.nih.gov/pubmed/30221662
http://dx.doi.org/10.3892/ijmm.2018.3866

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