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Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP)

Serine hydrolases play diverse roles in regulating host-pathogen interactions in a number of organisms, yet few have been characterized in the human pathogen Staphylococcus aureus. Here, we describe a chemical proteomic screen that identified 10 previously uncharacterized S. aureus serine hydrolases...

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Detalles Bibliográficos
Autores principales: Lentz, Christian S., Sheldon, Jessica R., Crawford, Lisa A., Cooper, Rachel, Garland, Megan, Amieva, Manuel R., Weerapana, Eranthie, Skaar, Eric P., Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202179/
https://www.ncbi.nlm.nih.gov/pubmed/29769740
http://dx.doi.org/10.1038/s41589-018-0060-1