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High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma

Due to the therapy resistance and frequent metastasis, pancreatic ductal adenocarcinoma(PDAC) remains one of the most malignant carcinoma. WNT7A, an important ligand of Wnt/β-catenin signaling pathways, has a controversial role in tumor development. The role of WNT7A in PDAC remains unclear. In this...

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Detalles Bibliográficos
Autores principales: Wu, Dong-jin, Jiang, Yong-sheng, He, Rui-zhe, Tao, Ling-ye, Yang, Min-wei, Fu, Xue-liang, Yang, Jiang-yu, Zhu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202314/
https://www.ncbi.nlm.nih.gov/pubmed/30361522
http://dx.doi.org/10.1038/s41598-018-34094-3