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GroEL/ES mediated the in vivo recovery of TRAIL inclusion bodies in Escherichia coli

Inclusion body (IB) formation generates substantial bio-waste in the pharmaceutical industry and remains a major challenge for heterologous protein expression. Although chaperones can be co-expressed to improve soluble protein yield, their contribution to IB processing in vivo has not been thoroughl...

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Detalles Bibliográficos
Autores principales: Wang, Zhanqing, Zhang, Min, Lv, Xin, Fan, Jiying, Zhang, Jian, Sun, Jing, Shen, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202318/
https://www.ncbi.nlm.nih.gov/pubmed/30361617
http://dx.doi.org/10.1038/s41598-018-34090-7