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GroEL/ES mediated the in vivo recovery of TRAIL inclusion bodies in Escherichia coli
Inclusion body (IB) formation generates substantial bio-waste in the pharmaceutical industry and remains a major challenge for heterologous protein expression. Although chaperones can be co-expressed to improve soluble protein yield, their contribution to IB processing in vivo has not been thoroughl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202318/ https://www.ncbi.nlm.nih.gov/pubmed/30361617 http://dx.doi.org/10.1038/s41598-018-34090-7 |